Saint-Rémy is also a cultural crossroads, with Alpilium offering varied shows and concerts. Art, particularly painting and sculpture, is celebrated at the Estrine Museum, in the art galleries in the city center and during the "Painters' Route" event.
Opened in February 2013, Alpilium is a place for cultural, festive, economic and associative events for Saint-Rémy de Provence. It is a hall allowing several configurations: show, hall, stand or standing audience.
The Alpilles Museum is housed in the Mistral de Mondragon mansion, a Renaissance monument. Since 1919, it has showcased the history and culture of the region through exhibitions of Archaeology, Natural Sciences, Ethnology, and Graphic Arts.